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Another widely used supplement in weight loss is garcinia cambogia. Garcinia cambogia is a small, sweet, purple fruit, also called the Malabar tamarind. This fruit contains hydroxycitric acid ("HCA"), a derivative of citric acid. Test-tube and animal research suggests that HCA may be helpful in weight loss because of its effects on metabolism. Animal studies have shown that HCA can suppress appetite and thereby encourage weight loss. It is thought to work by interfering with the body's ability to produce and store fat. It is known to inhibit the synthesis of lipids and fatty acids and lower the formation of LDL and triglycerides. When utilizing garcinia cambogia, the appetite is suppressed by promoting synthesis of glycogen. Glycogen is the stored form of glucose, one of the body's primary sources of energy. Increased glycogen production and storage is the body's normal way of signaling the brain's satiety center that enough food has been eaten. This has made garcinia a very effective herbal medicine for helping to control obesity and cholesterol. A typical dosage of HCA is 250 to 1,000 milligrams three (3) times daily. Products are often labeled garcinia cambogia and standardized to contain a fixed percentage of HCA, typically 50%, which is the dosage used in larger studies. No significant side effects have been reported from animal or human studies involving either fruit extracts or the concentrated chemical. |